Role Description
Pivot Path Solutions is seeking a Cardiovascular Research Scientist / Physiologist to support advanced research and development efforts in digital twin technologies for predictive medicine. This role will focus on developing and validating physiology-based models of the cardiovascular system, integrating clinical data with computational methods to simulate disease progression and treatment outcomes. The ideal candidate brings deep expertise in cardiovascular physiology, hemodynamics, and computational modeling, with the ability to translate biological systems into predictive, data-driven models. This position will play a critical role in supporting high-impact R&D initiatives aligned with federal research programs. This is a remote position.
Qualifications
• PhD in Biomedical Engineering, Physiology, Cardiovascular Science, Computational Biology or related field
• Strong background in cardiovascular physiology and hemodynamics
• Demonstrated ability to work with multimodal biomedical data
• Experience with peer-reviewed publications or funded research projects
Requirements
• Develop high-fidelity physiological models of the cardiovascular system, including blood flow dynamics, cardiac function, and systemic responses
• Translate clinical and experimental data (e.g., imaging, vitals, lab values) into computational models
• Support the design of digital twin architectures for patient-specific modeling
• Build and validate mechanistic (physics-based) models of:
• Hemorrhage and shock (acute conditions)
• Heart failure and chronic cardiovascular disease
• Collaborate on the development of reduced-order models (ROMs) for real-time simulation
• Conduct sensitivity analysis, uncertainty quantification, and model calibration
• Collaborate with clinicians to ensure biological and clinical relevance of models
• Support development of validation strategies, including comparison against human or animal data
• Contribute to study design and experimental protocols as needed
Benefits
• Collaborate on high-impact federal innovation programs
• Flexible, entrepreneurial engagement model
• Opportunity to shape next-generation digital twin initiatives in mission-critical environments
• Direct access to executive leadership and capture strategy discussions
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